The Technology Licensing Office’s bi-weekly market research report highlights emerging trends, market signals, and industry developments that may inform research and commercialization strategy across the University of Utah. Each edition curates timely insights from key sectors to help faculty, researchers, and innovation partners identify opportunities, anticipate market needs, and align discoveries with real-world demand.

Emerging Market Insights

Direct In-Vivo CAR-T Engineering Targets the Manufacturing Bottleneck in Cell Therapy

In-vivo CAR-T platforms are shifting cell therapy from centralized ex-vivo manufacturing to direct immune-cell programming inside the patient using targeted LNPs, circular RNA, and engineered viral vectors. Now entering the clinic with first-in-human readouts and major pharma investment, the approach addresses high cost, long vein-to-vein timelines, lymphodepletion burden, and limited access to conventional CAR-T therapy. Faculty can align with this shift by engineering T-cell-selective delivery systems, optimizing transient expression and safety switches, validating biodistribution and immune-toxicity models, and developing scalable CMC controls for oncology and autoimmune applications.

See also: Legend’s experimental cell therapy shows promise in blood cancer patients

Compound Flood Research Shifts Toward Integrated Vulnerability, Loss Validation, and Decision-Ready Tools

Compound flood research is advancing from hazard identification toward integration and translation: coupling multi-driver flood models with spatially resolved social vulnerability, validating isolated versus compound loss pathways against claims and insurance data, and co-creating operational tools for resilience planning, emergency management, and risk transfer. Faculty can align by developing empirically tested, end-user-informed models that connect interacting flood drivers to real-world social and economic impacts.

Upcoming Webinars

Global Harmonization: Insights from the ICH CGT Discussion Group – Wednesday, June 24, 2026

This expert-led webinar explores the Cell & Gene Therapy Discussion Group’s mission to map global regulatory frameworks, identify critical areas of divergence, and propose a strategic roadmap for international harmonization.

Connecticut Sea Grant: Compound Flood Hazard Assessment Mapper Webinar – Thursday, June 11, 2026

During this virtual webinar, geared towards municipal staff, state agencies, and other partners, participants will learn how the United States Geological Survey (USGS) developed this new tool and how to utilize it in planning and decision-making.

Tools & Resources

Access additional market information through powerful tools available from the J. Willard Marriott Library:

Markets and Markets – Comprehensive market reports, with competitive intelligence and trends

BCC Research – Detailed market forecasting and industry analysis

Factiva – Global news and business information

Pitchbook – Private market and investment data

Researchers can contact the Technology Licensing Office (TLO), Eccles Health Science Library, J. Willard Marriott Library, or Center for Medical Innovation (CMI) for tailored market information.

Need help getting started?

Explore our full Market Research for Inventors page for tools, examples, and a step-by-step PDF guide to walk you through the process.

This article was originally published on the Technology Licensing Office site.