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Sep 22 - Oct 28

DTRA-MTEC RFP Announcement: “Advancing Biodefense Readiness: On-Demand Biologics, Automated Threat Detection, and Alternative MCM Testing in High Containment”

Extramural Funding

On September 22, 2025, the Medical Technology Enterprise Consortium (MTEC), in support of the Defense Threat Reduction Agency (DTRA), posted the announcement for the "Advancing Biodefense Readiness: On-Demand Biologics, Automated Threat Detection, and Alternative for Testing Medical Countermeasures in High Containment" effort (also known as the DTRA Multi-Topic) on the MTEC website and a notice will be posted on http://www.sam.gov/ to notify interested parties. This announcement is for a Request for Project Proposals (RPP) focused on advancing the following medical and bioengineering technologies:

  • Focus Area #1: Biologics On Demand
  • Focus Area #2: Automated Clinical and/or Environmental Sampling, Sequencing, and Analysis
  • Focus Area #3: Alternative Methods for Testing Medical Countermeasures (MCMs) in High Containment
  • Focus Area #4: Microphysiological Alternatives for Gauging Pretreatment Immunogenicity and Efficacy (MAGPIE)

White Papers are due on October 28, 2025 at Noon Eastern Time.

Please visit the MTEC website at https://mtec-sc.org/solicitations/25-10-dtra_multi to view the RPP, which includes additional information on Technical Objectives and Solution Requirements for each Focus Area.

Please note, MTEC membership will be required for submission of White Papers to the RPP. If you are not currently a member, please visit http://mtec-sc.org/join.

For inquiries, please direct your correspondence to the following contacts:

  • Membership questions should be directed to MTEC Member Relations, Ms. Kim Olsen, kim.olsen@mtec-sc.org
  • Questions concerning contractual, cost or pricing related to this RPP should be directed to the MTEC contracts team at contracts@mtec-sc.org
  • Technical and all other questions should be directed to the MTEC Chief Science Officer, Dr. Lauren Palestrini, Ph.D., lauren.palestrini@mtec-sc.org